CleanSpace Cleanrooms fixes air quality issue for Single Quantum

CleanSpace Cleanrooms has helped Single Quantum fix an air quality issue in its hi-tech cleanroom.

Single Quantum is a provider of “single photon detection technology”.

The Netherlands-based company’s light-sensitive productions have now been used by more than 200 academic and industrial laboratories worldwide to perform complex optical measurements.

Netherlands-based CleanSpace (not to be confused with the US-based company), was brought on board after a single large lab space was divided into several smaller spaces at Single Quantum.

Following this change, there started to be complaints about the air quality in these new spaces in Delft.

“There appeared to be increased production rejection due to regular contamination of the measuring equipment,” CleanSpace explained. “Single Quantum then asked CleanSpace Cleanrooms to what extent this could be prevented in a cost-effective manner.”

CleanSpace’s work included improving the air quality in the lab areas and protecting the process.

CleanSpace explained that it distributed the available air over the different rooms, so that each room had its own cooled and filtered air intake.

“In order to properly remove the heavier particles in particular, a low extraction of air from the rooms was desirable,” the company explained. “For the extra clean, particle-free production area, we recommended a wall-to-wall downflow unit, which allowed the various process steps to be protected against particle contamination under an extremely clean laminar air flow.

CleanSpace also advised that users in critical areas wear adequate, non-marking cleanroom clothing.

At the end of January 2024, the project was delivered and Single Quantum was satisfied.

Shibaura Machine Company introduces medical moulding press for cleanroom environments

The first medical-specific all-electric injection molding machine from Shibaura Machine Company, America will be introduced to the North American market during Plastec West 2024.

“For years, medical device manufacturers have been using our general purpose ECSXIII machine to mould a variety of products,” said Chad Clawson, Key Accounts Sales Manager for Medical Casting/Molding Division at Shibaura. “Our new medical-specific machine offers the same speed and functionality as other ECSXIII models, with enhancements that are ideal for medical moulding and cleanroom environments.”

These enhancements include:

  • Plated platens to control particulates and contamination
  • Stainless steel guarding and panels ideal for cleanroom environments
  • Raised frame for easy access to clean below the machine
  • Special NFS H1 Certified lubrication grease
  • Extended ejector stroke (+30 mm)

At Plastec West, Shibaura will use the new EC110SXIII medical machine to produce medical pipettes. Fully integrated with the EC110SXIII will be a Mold-Masters hot runner controller and Mold-Masters water manifold system, which are available as optional add-ons.

The latest addition to Shibaura’s popular ECSXIII series of all-electrics, the new medical machine delivers fast injection speeds and dry cycle times, ensures longer mould life and provides uniform clamping force, for greater productivity, flexibility and versatility.

The machine also features the same user-friendly V70 controller built into all ECSXIII models, making it easy for operators to decrease mould set up time, optimise cycle times, analyze part defects, troubleshoot defects and more.

Included with the new machine is a full year subscription to machiNetCloud, Shibaura’s exclusive industrial IoT service providing manufacturers with remote, real-time access to machine data so they can control validated processes for molded components anytime, from any location.

The new medical-specific EC110SXIII is currently available in 110 US tons, with larger sizes to be available in the future.

ABN uses SterCube VELOX outdoor unit for Grade D nuclear cleanroom

ABN Cleanroom Technology, a provider of pre-engineered cleanroom solutions for industries such as healthcare and pharma, has reached the end phase of constructing a new SterCube VELOX outdoor cleanroom unit.

The project entails a SterCube VELOX with multiple hot labs and QC labs on the inside.

SterCube VELOX is a mobile cleanroom solution for outdoor use, meant for high-end studies at nuclear sites, so it is often called a Lab2Cube.

The classification of this cleanroom is cGMP Grade D.

To create a VELOX, ABN Cleanroom Technology configured several SteriCube compartments to become a fully functional cleanroom area with all needed utilities for a critical nuclear environment such as CDA, O2, N2, and Denim Water.

Jo Nelissen, CEO of ABN Cleanroom Technology, said: “The great thing about our SteriCube VELOX solutions, is that we never have to start our projects from scratch, but that we can configure our virtual and physical building blocks that are off-the-shelf available.”

“With this project approach, we are able to deliver a fully operational cleanroom and BSL on site in just 12 weeks -from quotation to hand-over to the customer,” Nelissen continued.

“SteriCube VELOX is currently one of our best-selling products due to its highly configurable and temporary character. We have previously installed multiple of these units on nuclear sites, which makes it a proven solution for operators working in that field,” Nelissen concluded.

The cleanroom is assembled in ABN Cleanroom Technology’s manufacturing hall and transported to customers in separate parts.

Further, as a result of its design for modularity and circularity, there was no waste of materials when separating the units for transport.

At the customer’s site, the separate parts were assembled back together after which ABN Cleanroom Technology’s Validation Department started its validation activities.

Also, a SteriCube always comes with an online monitoring system, which in this case was CleanConnect.

This allows the nuclear operator to always have insights in the parameters of the cleanroom area.

In addition, ABN Cleanroom Technology pointed out that in this type of working environment, safety is crucial. Therefore, measurements need to be real-time with alarms going on when environmental limits are exceeded.

LIFE places cleanroom order to work on next-gen Continuous Glucose Monitor

Lifecare AS (LIFE), a clinical-stage medical sensor company, which is developing the next-generation Continuous Glucose Monitor (CGM), has disclosed that it has placed the purchase order for a cleanroom.

In LIFE’s investor communication, the company announced the launch of an automated production line by the end of Q2 2024. Also in the investor communication, the automated production line was set as a major milestone.

Joacim Holter, CEO of LIFE, said: “The cleanroom is now purchased as another step toward the company’s upcoming automated pilot production. The cleanroom will be delivered and installed in Q2 2024.”

Cleanrooms are always required where the airborne particles are likely to contaminate the final product.

LIFE’s cleanroom, which holds an ISO Class 7 standard, will ensure that the airborne particles are maintained at a very low concentration to not interfere with crucial functions of sensor components during sensor manufacturing.

The sensor components consist of micro and nano technologies sensitive to particles.

The airborne particles could potentially impact the functionality of the sensor by blocking the nano filtration layers and subsequent flow of the substances in and out of sensor cavities.

The cleanroom was planned and designed in 2023 by evaluation of various process maps of LIFE’s automated manufacturing equipment and is another step toward the product launch in the veterinary market.

In recent months, LIFE has made strategically important purchases of production equipment.

A purchase order has been made for Scanning Electron Microscope from the German company Carl Zeiss AG and software from the same supplier.

In addition, a purchase order has been placed for a BioScaffolder (BS 3.3) and a customised Nano-Plotter (NP 2.1) from the German supplier GeSiM mbH.

Both suppliers of this cornerstone equipment have confirmed delivery in Q2 2024.

Holter said: “This is the last important investment to facilitate automated pilot production in the next quarter. All the equipment will now arrive in Q2 within the deadlines,” Holter concluded.